Basic concepts of immunology. Structure of antigens; antigenic determinants and cellular response. Structure and activation of the T-cell antigen receptor. Structure and classification of immunoglobulins and antibodies. Mechanism and theories of antibodies formation. Antigen and antibody interactions. Role of lymphoid tissues and thymus in immuno-responses. Genetic basis of antibody diversity. The complement system in immune response. Hypersensitivity, immunopathology, autoimmunity, tumor and transplantation immunology. Immunochemical techniques; Haemagglutination and complement fixation, precipitation reactions, immunoblotting, isolation of lymphocyte population, cytotoxic assay etc
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